Cell-Permeable Succinate Increases Mitochondrial Membrane Potential and Glycolysis in Leigh Syndrome Patient Fibroblasts.

When the uncoupler, cyanide p -trifluoromethoxyphenylhydrazone (FCCP), was added to depolarize the mitochondria, all cell lines responded to this treatment by exhibiting a decreasing trend in MMP relative to the TMRE only treatment ( Supplementary Materials Figures S2–S4c,d and Figures S3 and S4g,h ).

also in 47,180 other papers