Aqueous Extract of Cocoa Phenolic Compounds Protects Differentiated Neuroblastoma SH-SY5Y Cells from Oxidative Stress.

As in the case of GPx, pre-treatment for 3 h with all four concentrations of cocoa extract significantly recovered GR activity in a dose-dependent manner between a slight (barely significant) decrease at 25 μg/mL and a through recovery of basal values at 50 and 100 ug/mL, being 200 μg/mL more effective than 25 but less effective than the two lower concentrations ( Figure 7 ).

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