Oestrogen Activates the MAP3K1 Cascade and β-Catenin to Promote Granulosa-like Cell Fate in a Human Testis-Derived Cell Line.

While AKT1 had no detectable changes to its phosphorylation or abundance, it demonstrated an overall trend towards activation at both timepoints where all but one of its substrates had increased phosphorylation; furthermore, it had a large number of protein-level substrates with altered phosphorylation, suggesting a change to its activity.

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