In coculture, the metabolic activity of CYP2C19 was significantly decreased, and that of CYP3A4 ( p = 0.0599) showed an increasing trend, but the metabolic activity of other enzymes showed no difference compared to that of the monoculture ( Figure 5 A).
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A Kinetic Pump Integrated Microfluidic Plate (KIM-Plate) with High Usability for Cell Culture-Based Multiorgan Microphysiological Systems.
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