Evaluating general markers for neuroinflammation indicates a significant upregulation of the astrocyte marker Gfap ( t 9 = 2.57, p = 0.03) and borderline significance for oxidative stress ( Nox2 : t 7 = 2.11, p = 0.07) and microglial activity (Iba1: t 9 = 1.94, p = 0.08).
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<i>A20</i>/<i>TNFAIP3</i> heterozygosity predisposes to behavioral symptoms in a mouse model for neuropsychiatric lupus.
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