nsP4 Is a Major Determinant of Alphavirus Replicase Activity and Template Selectivity.

J Virol · 2021 · PMC8475546 · PMID 34319783

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closest p · 0.2× alpha

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highly significantP < 0.01actually significant

2B and C and 3A ), while the increase in ratio to 8:1 (nsP4:P123 expression plasmid) resulted in highly significant increases of both template RNA replication (approximately 40-fold, P < 0.01) and transcription (approximately 30-fold, P < 0.01).

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