Effect of Moderately but Persistently Elevated Lipid Levels on Risks of Stroke and Myocardial Infarction in Young Korean Adults.

21 Furthermore, there is evidence of increasing stroke rates for individuals aged <50 years, despite a decreasing trend for stroke in the general population since 1950. 22 Importantly, in stroke survivors aged 18 to 49 years, long‐term mortality (with up to 15 years of follow‐up) was significantly higher than that in the general population, emphasizing the importance of preventing the development of stroke in young adults. 23 However, because of limited evidence, few recommendations exist on risk stratification and indications for primary preventative therapy in young adults, except for statin therapy for those with severe primary hypercholesterolemia, defined as LDL‐C ≥190 mg/dL.

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