Our systematic identification yielded highly significant supportive evidence for the existence of dietary derived plant miRNA in humans and animals and subsequent careful comparison of plant miRNAs identified in blood and tissue samples of herbivores versus carnivores and omniviores further codified the that plant-derived miRNAs originate from specific diets and underscore the possibility for cross-kingdom communication and regulation via plant-derived miRNAs.
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Large-scale identification of extracellular plant miRNAs in mammals implicates their dietary intake.
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