Genetic dissection of complex traits using hierarchical biological knowledge.

PLoS Comput Biol · 2021 · PMC8480841 · PMID 34534210

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may not be significantno p-value reported

These findings suggest that our ontotype models can detect genetic associations based on the convergent effects of many SNVs, even when the marginal effects of each of these SNVs may not be significant.

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