The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure.

Neurobiol Stress · 2021 · PMC8482287 · PMID 34621920

Europe PMC DOI

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highly significantp = 1.65*10–6actually significant

Using data from an independent sample that identified dexamethasone-responsive CpGs on a genome-wide level ( Provençal et al., 2020 ), we observed a highly significant enrichment of dexamethasone-responsive CpGs within the PedBE clock (Fisher's Exact: p = 1.65*10–6, Odds Ratio = 4.36).

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