Using density of antecedent events and trajectory path analysis to investigate family-correlated patterns of onset of bipolar I disorder: a comparison of cohorts from Europe and USA.

Int J Bipolar Disord · 2021 · PMC8484401 · PMID 34595593

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of borderline significanceno p-value reported

Median AAO in those with a depressive onset polarity was associated with the same two variables (HR for comorbidities: 0.44; 95% CI: 0.29, 0.68; HR for year of birth: 1.29; 95% CI: 1.04, 1.58); sex was of borderline significance in this model (HR for male sex: 1.28; 95% CI: 0.94, 1.68).

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