The scale and relevance of LPP-associated biomarkers is likely to be significant in the future, as LPP complexes are estimated in serum and plasma at concentrations of the 10 16 individual LPPs/mL (based on Jens, Circulation Research 2017 121:920–922, roughly 10 7 -fold more concentrated than EVs, for example).
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EV Translational Horizons as Viewed Across the Complex Landscape of Liquid Biopsies.
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