Recurrent Severe Preschool Wheeze: From Prespecified Diagnostic Labels to Underlying Endotypes.

There was a highly significant difference in cluster allocation between the RSW and NWRD groups, in that children with RSW were approximately equally distributed across the pathophysiological clusters, whereas the majority of children with NWRD (60%) were assigned to cluster 4; not a single child with NWRD was assigned to cluster 1.

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