Analysis of Immune Landscape Reveals Prognostic Significance of Cytotoxic CD4<sup>+</sup> T Cells in the Central Region of pMMR CRC.

Front Oncol · 2021 · PMC8493090 · PMID 34631551

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an increasing trendno p-value reported

It turned out that after neoadjuvant chemotherapy, the number of immune cells distributed in CT, especially the sCT subregion showed an increasing trend, among which CD8 + T cells, CD8 + GzmB + T cells, CD4 + GzmB + T cells, and CD66b + granulocytes had significant statistical differences.

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