Detection of Cerebrospinal Fluid Neurofilament Light Chain as a Marker for Alpha-Synucleinopathies.

Front Aging Neurosci · 2021 · PMC8493247 · PMID 34630068

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highly significantno p-value reported

When we determined CSF-NfL, a known marker for several neurodegenerative diseases, reflecting the neuroaxonal damage ( Holmberg et al., 1998 ; Petzold, 2005 ), we obtained a highly significant increase of NfL levels in patients with DLB and MSA compared to those with PD and controls.

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