Cancer-associated fibroblasts-derived exosomal miR-3656 promotes the development and progression of esophageal squamous cell carcinoma via the ACAP2/PI3K-AKT signaling pathway.

Int J Biol Sci · 2021 · PMC8495391 · PMID 34671193

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an increasing trendno p-value reported

The number of ESCC cases has shown an increasing trend year by year in East Asia, South Africa, East Africa and Northern Europe 4 , while less than 20% of advanced EC patients survive for 5 years 5 , 6 .

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