Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by coding sequence composition and mRNA localization.

Genome Biol · 2021 · PMC8496106 · PMID 34615539

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In addition, we see a highly significant global reduction in the translational efficiency of ER-target mRNAs following CNOT1 depletion (Fig. 3 F), suggesting the Ccr4-Not complex specifically plays a role in the regulation of mRNAs that localize to the ER to be translated.

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