Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.

Weighted Gene Co-expression Network Analysis (WGCNA) identified two gene modules that were significantly different between APOE −/− and controls (yellow and green, p = 0.01) and two gene modules that were marginally significant (red and blue, p = 0.05) (Fig. 2 a).

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