Estimating tumor mutational burden across multiple cancer types using whole-exome sequencing.

Ann Transl Med · 2021 · PMC8506705 · PMID 34733989

Europe PMC DOI

hedged sentence

0.0100

closest p · 0.2× alpha

0.0100

boldest claim

The sentences

extremely significantP=0.01actually significant

In CRC, the separation between the TMB-high and TMB-low groups was extremely significant and the TMB-high group showed a survival benefit after receiving ICI treatment [P=0.01, HR =0.31, 95% CI: 0.15–0.68] ( Figure 2E ).

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