Stroma AReactive Invasion Front Areas (SARIFA)-A New Easily to Determine Biomarker in Colon Cancer-Results of a Retrospective Study.

Cancers (Basel) · 2021 · PMC8508517 · PMID 34638364

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0650

boldest claim

The sentences

just failed significancep = 0.058so close (0.05 < p ≤ 0.1)

highly significantno p-value reported

In the pT3 subgroup analysis of group B, SARIFA was a highly significant prognostic marker in the univariate analysis and just failed significance in the multivariate analysis (metastasis: p = 0.058, overall-survival: p = 0.082).

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a trend toward significancep = 0.065so close (0.05 < p ≤ 0.1)

Despite the numerous associations of SARIFA with a poor prognosis, significant association of SARIFA with colon-cancer-specific survival ( p = 0.008) could be solely demonstrated in group A, whereas group B only exhibited a trend toward significance ( p = 0.065).

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