Deletion of Neuronal CuZnSOD Accelerates Age-Associated Muscle Mitochondria and Calcium Handling Dysfunction That Is Independent of Denervation and Precedes Sarcopenia.

Int J Mol Sci · 2021 · PMC8509582 · PMID 34639076

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highly significantno p-value reported

Large variation in the properties of the ICT displayed for muscles of middle-aged i-mn- Sod1 -/- mice prevented significance when analyzed by two factor ANOVA; however, when i-mn- Sod1 -/- and control muscles were compared by t -test, the differences in both ICT peak and ICT FWHM were highly significant for middle-aged mice.

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