The Relationship of Glutathione-<i>S</i>-Transferase and Multi-Drug Resistance-Related Protein 1 in Nitric Oxide (NO) Transport and Storage.

Molecules · 2021 · PMC8510172 · PMID 34641326

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The Potential Intermediary or Storage Role of DNICs by GST Enzymes The role of GSTs in detoxification may be significant in NO metabolism, given that the binding of with DNICs directly to GSTs results in a markedly increased half-life (4.5–8 h) [ 210 ] and a significantly increased half-life than “free NO” (i.e., 2 ms to 2 s) [ 211 ].

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