Complement Potentiates Immune Sensing of HIV-1 and Early Type I Interferon Responses.

mBio · 2021 · PMC8510548 · PMID 34634939

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highly significantno p-value reported

In contrast, the highly significant increase in IFN-β mRNA expression in HIV-C-DCs was completely abrogated or significantly down-modulated in RIG-I- and MDA5-silenced DCs upon HIV-C treatment ( Fig. 4e , left; RIG-I and MDA5 siRNA).

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