The selective degradation of sirtuins via macroautophagy in the MPP<sup>+</sup> model of Parkinson's disease is promoted by conserved oxidation sites.

Cell Death Discov · 2021 · PMC8511006 · PMID 34642296

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borderline significantno p-value reported

None of the SIRTs exhibited a smaller cytosolic fraction under MPP + or PHT/MPP + treatment at baseline, and except for the borderline significant SIRT3, BafA1 treatment caused no shift in MPP + -treated cells.

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