Gene Expression Analysis in Four Dogs With Canine Pemphigus Clinical Subtypes Reveals B Cell Signatures and Immune Activation Pathways Similar to Human Disease.

P < 0.05 were considered significant, and P < 0.01 were considered highly significant.

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We also examined genes that were trending toward significance, as these might provide insights into additional genes driving pathogenesis of canine pemphigus, but were under-powered in our study of four cases ( Figure 1C ).

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