Hepatic transcriptomic profiling revealed a nonsignificant trend to increased Col1a1 and increased Tgfb, and Desmin mRNA abundance in chow-fed Mttp-IKO mice, along with increased F4/80 mRNA ( Fig. 6 D).
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Inhibition of chylomicron assembly leads to dissociation of hepatic steatosis from inflammation and fibrosis.
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