Changes in antibiotic consumption, AMR and Clostridioides difficile infections in a large tertiary-care center following the implementation of institution-specific guidelines for antimicrobial therapy: A nine-year interrupted time series study.

PLoS One · 2021 · PMC8516227 · PMID 34648594

Europe PMC DOI

hedged sentence

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

a positive trendp<0.001actually significant

The intervention was associated with an initial reduction of -1.8 (-2.9 to -0.7, p<0.01) followed by a positive trend with a trend change of +0.13 per month (95%CI 0.08 to 0.19, p<0.001).

also in 11,005 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.