Molecular Insight into the Effect of a Single-Nucleotide Polymorphic Variation on the Structure and Dynamics of Methionine Synthase Reductase and Its Association with Neural Tube Defects.

Therefore, the present study also highlights the applicability of molecular dynamics simulation and bioinformatics to screen out highly significant genetic markers for better disease prognosis. 4 Experimental Section 4.1 Study Sample All the samples (case, n = 62; control, n = 73) were collected from the Department of Neonatology of Seth Sukhlal Karnani Memorial Hospital (SSKM) and the Institute of Post-Graduate Medical Education and Research (IPGMER), Kolkata, India, during the period of January 2014–August 2017 with prior ethical approval (memo no.

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