A <i>docked</i> mutation phenocopies <i>dumpy</i> oblique alleles <i>via</i> altered vesicle trafficking.

Furthermore, the location of this variation is highly significant, because the hydrophilic N-terminal end of YIP family members is predicted to project into the cytoplasm ( Matern et al., 2000 ; Yang, Matern & Gallwitz, 1998 ), where it interacts with a variety of other proteins such as Rab-family GTPases that play crucial modulatory roles in membrane dynamics ( Yang, Matern & Gallwitz, 1998 ).

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