Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.

Proc Natl Acad Sci U S A · 2021 · PMC8521679 · PMID 34611019

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highly significantno p-value reported

We also found CD8 T cells present in non-T1D islets, albeit in low numbers, with a highly significant difference between preproinsulin reactive TCRs in T1D (26/142 TCR) versus non-T1D (1/71 TCR) islets.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.