Evaluation of AT-752, a Double Prodrug of a Guanosine Nucleotide Analog with <i>In Vitro</i> and <i>In Vivo</i> Activity against Dengue and Other Flaviviruses.

Antimicrob Agents Chemother · 2021 · PMC8522752 · PMID 34424050

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highly significantno p-value reported

Nevertheless, the statistically significant differences in viremia observed on days 6 and 8 pi, combined with the significant effects on prevention of weight loss and deterioration of health score on days 3 through 8 (last day of surviving controls) and on the highly significant prolongation of survival, attest to the efficacy of AT-752.

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