Because of the very crucial roles of this essential metal in many metabolic activities in the body, downregulation of its level as observed in children with ASD in this study in comparison to what obtained in NT children may be significant in the observed dysfunction and clinical symptoms associated with ASD.
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Cu ratio ( r = 0.907; p = 0.000). Table 4 : Correlation of Zn/Cu ratio with Oxidative indices in Children with ASD No significant correlations were observed among markers of oxidative stress including with Zn/Cu ratio in children with ASD except between OSI and TAC ( r = -0.983, p = 0.000) where a highly significant negative correlation was obtained.