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The relationship between vancomycin AUC/MIC and trough concentration, age, dose, renal function in Chinese critically ill pediatric patients.

Pharmacol Res Perspect · 2021 · PMC8525138 · PMID 34664790

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a decreasing trendno p-value reported
Half‐life was significantly longer in neonates and showed a decreasing trend in infants and children.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.