Plasma Concentration of 12-Hydroxyeicosatetraenoic Acid, Single Nucleotide Polymorphisms of 12-Lipooxygenase Gene and Vaso-Occlusion in Sickle Cell Disease.

Front Genome Ed · 2021 · PMC8525407 · PMID 34713264

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highly significantp < 0.0001actually significant

Correlation of VOE Score with Plasma Concentration of 12-HETE, TNF-alpha and IL-1β There was a strong and highly significant direct correlation between vaso-occlusive events score and plasma concentration of the pro-inflammatory molecule 12-HETE (r = 0.65, p < 0.0001), Table 3 .

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