Reduced Dopamine Signaling Impacts Pyramidal Neuron Excitability in Mouse Motor Cortex.

eNeuro · 2021 · PMC8525657 · PMID 34556558

Europe PMC DOI

hedged sentence

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

trending toward significancep = 0.068so close (0.05 < p ≤ 0.1)

Stereological counts of TH + boutons in M1 showed that the 6OHDA lesion significantly reduced TH + boutons in ipsilateral L5 and reduction trending toward significance in ipsilateral L2/3 [ Fig. 7 C , D ; vehicle L2/3, 1.012 ± 0.13; 6OHDA L2/3, 0.63 ± 0.10 ( p = 0.068); vehicle L5, 1.00 ± 0.13; 6OHDA L5, 0.46 ± 0.079 ( p = 0.017)], indicating that the 6OHDA injection was effective.

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