An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats.

NPJ Vaccines · 2021 · PMC8528862 · PMID 34671047

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highly significantno p-value reported

The licensure of IBV vaccines requires not only the demonstration of protection from clinical disease but also a highly significant reduction of virus replication in the trachea.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.