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Treatment failure to sodium stibogluconate in cutaneous leishmaniasis: A challenge to infection control and disease elimination.

PLoS One · 2021 · PMC8535432 · PMID 34679130

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may not be significantno p-value reported
Even though the levels of arsenic in agrochemicals and fish seem to be much lower than the maximum contaminant levels and may not be significant or toxic when considered individually, it might be postulated that study participants may have been chronically exposed to sub-lethal levels of arsenic with the development of arsenic-resistant parasite strains that might be cross-resistant to antimony therapy [ 46 , 68 , 70 – 75 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.