A recent meta-analysis from Ethiopia and Europe also noted an increasing trend of G2P[4], G9P[8], and/or G12P[8] and other previously uncommon genotypes not fully represented in the monovalent Rotarix vaccine that covers the G1P[8] strain [ 70 , 94 ].
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Prevalence, Pattern and Genetic Diversity of Rotaviruses among Children under 5 Years of Age with Acute Gastroenteritis in South Africa: A Systematic Review and Meta-Analysis.
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However, a further look at the change in the geographical distribution of RV infection revealed a significant increase in diarrheal cases in the KwaZulu-Natal and Western Cape Provinces where a decreasing trend in vaccine coverage has been documented.