A Presurgical Study of Curcumin Combined with Anthocyanin Supplements in Patients with Colorectal Adenomatous Polyps.

Int J Mol Sci · 2021 · PMC8539981 · PMID 34681684

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borderline significantno p-value reported

When comparing pre- and post-treatment levels within each group, the combination of anthocyanins and curcumin resulted in a borderline significant reduction of the NF-κB expression, assessed by immunohistochemistry (IHC), in adenoma tissue (geometric mean ratio (GMR): 0.72; 95% confidence interval (CI): 0.51–1.00; p -value: 0.05) and a trend towards a reduction for Ki-67 (GMR: 0.73; 95% CI: 0.50–1.08; p -value: 0.11).

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