In contrast to TMZ, which had no effect on caspase 3 activity, application of both TCS and LY294002 resulted in a partially significant increase of caspase 3 activity in LN-18 adherent cells ( Figure 5 C) and neurospheres ( Figure 5 D), depending on the concentration used.
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PIM1 Inhibition Affects Glioblastoma Stem Cell Behavior and Kills Glioblastoma Stem-like Cells.
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