Barely Significant
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Effect of Tafamidis on Serum Transthyretin Levels in Non-Trial Patients With Transthyretin Amyloid Cardiomyopathy.

JACC CardioOncol · 2021 · PMC8543137 · PMID 34729530

Europe PMCDOI
1
hedged sentence
0.0570
closest p · 1.1× alpha
0.0570
boldest claim

The sentences

just failed to reach statistical significanceP = 0.057so close (0.05 < p ≤ 0.1)
The increase in high-sensitivity troponin between baseline and follow-up just failed to reach statistical significance (P = 0.057) Discussion These data, derived from a consecutive cohort of non-trial patients with cardiomyopathy caused by ATTR, show a significant increase in TTR levels after the initiation of tafamidis, with maintenance of this increase in the group of patients who had a second post-tafamidis visit at which a TTR level was drawn.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.