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Extrahepatic biliary obstruction secondary to metastatic esophageal squamous cell carcinoma: An unusual presentation of Courvoisier's law.

Clin Case Rep · 2021 · PMC8552081 · PMID 34745625

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an increasing trendno p-value reported
Squamous cell carcinoma is the most common subtype worldwide with an increasing trend of the adenocarcinoma subtype becoming more prevalent in developed countries. 1 Risk factors for squamous cell carcinoma include low socioeconomic status, tobacco use, alcohol, hot beverages, nitrosamines, and vitamin C, E, and Folate deficiencies. 1 The presenting signs and symptoms of advanced esophageal cancer are secondary to decreasing size of the esophageal lumen diameter and are most commonly progressive dysphagia and unintentional weight loss due to changes in diet to accommodate dysphagia and tumor related anorexia.

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