Pediatric sepsis research in low- and middle-income countries: overcoming challenges.

( 5 ) Another systematic review and metanalysis, that included 94 studies and 7,561 pediatric patients with sepsis and organ dysfunctions, showed a decreasing trend in lethality for the period between 1980 and 2016, however, has also shown that the mortality remains high (25%) and is larger in LMIC: the chance of a child with sepsis dying in developing countries is four times higher than in developed countries.

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