Comparative clinical benefits of systemic adjuvant therapy for paradigm solid tumors.

Cancer Treat Rev · 2013 · PMC8555872 · PMID 22520262

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highly significantno p-value reported

101 – 107 Meta-analysis of 12 randomized adjuvant trials was therefore pursued and confirmed highly significant reduction in recurrence with IFN-α over observation and a trend towards improved benefit with increasing dosage. 107 A larger individual patient data meta-analysis of 13 randomized trials showed a statistically significant benefit for event-free survival (EFS) (odds ratio [OR] = 0.87; 95% CI 0.81–0

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