Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels.

Mol Metab · 2021 · PMC8556519 · PMID 34610354

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highly significantno p-value reported

In hypothyroid mice, leptin induced a highly significant increase in Dio1 and Tbg expression at 30 °C but not at 21 °C, compared with the saline-treated controls.

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