Barely Significant
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Metformin in the management of fibrocystic breast disease: a placebo-controlled randomized clinical trial.

Daru · 2021 · PMC8557102 · PMID 34719004

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may be significantno p-value reported
The nodularity and lumpiness that accompany FCD may interfere with the correct detection of breast masses, and mastalgia may be significant enough to affect the patient’s activities and quality of life or cause concern and worry about breast health.

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