highly significantp < 0.001
extremely significantp > 0.05
The significance of differences in the comparison of data was calculated using the two-sided Student`s t test, with p < 0.05 rated as statistically significant) (*), p < 0.01 as highly significant (**) and p < 0.001 as extremely significant (***); p > 0.05 was rated as not significant (n.s.).