Gut Microbiota-Derived Metabolites in Colorectal Cancer: The Bad and the Challenges.

Front Oncol · 2021 · PMC8558397 · PMID 34733783

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may be significantno p-value reported

The liver kinase B1 (LKB1)-dependent activation of AMPK and reduction of mammalian target of rapamycin (mTOR) activity may be significant contributors to the inhibitory effects of metformin on cancer cell growth and proliferation ( 151 ).

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