Role of Cardiac AMP-Activated Protein Kinase in a Non-pathological Setting: Evidence From Cardiomyocyte-Specific, Inducible AMP-Activated Protein Kinase α1α2-Knockout Mice.

Front Cell Dev Biol · 2021 · PMC8558539 · PMID 34733845

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

at the limit of significancep = 0.08so close (0.05 < p ≤ 0.1)

Effects of exercise, e.g., decreased ATP or increased ADP/ATP and AMP/ATP ratios, were at the limit of significance ( p = 0.08, p = 0.06, and p = 0.10, respectively).

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a decreasing trendno p-value reported

Under these conditions, after exercise, there was only a decreasing trend in energy reserve in both genotypes, and no significant activating AMPK phosphorylation, neither in KO nor CTR animals.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.