Does it actually act on other SNAREs? This is important because the clearest argument for this brief study being viewed as a highly significant research advance (over their previous work) is the implication that the unexpected direct role of Sec17/18 can now be considered likely to take place in other, if not all, SNARE-mediated fusion events. 6.
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Fusion of tethered membranes can be driven by Sec18/NSF and Sec17/αSNAP without HOPS.
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